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wiki:autolit:meta_analytical_extraction:extract [2023/06/27 21:02]
jthurnham created
wiki:autolit:meta_analytical_extraction:extract [2024/05/17 13:32] (current)
jthurnham [1. Navigate to Extraction]
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-====== Meta-Analytical Extraction (previously named Extraction) ======+====== Meta-Analytical Data Extraction ======
  
-Extraction enables you to gather quantitative data from underlying studies. In short, after configuring your Interventions and Data Elements on the Configure Study Tags page, you can extract dichotomous, categorical, or continuous data across any number of timepoints from all included studies.+Once you have [[:wiki:autolit:meta_analytical_extraction:configure|configured]] your Interventions and Data Elements, you are ready to extract data from all included studies in the nest.
  
-<WRAP center round info 60%> We are currently in the process of transitioning our module names with the goal of making the AutoLit workflow easier to understand for first-time users.+===== Steps for Data Extraction: =====
  
-**Tagging** is now **Extraction**, **Extraction** is now **Meta-Analytical Extraction**, and **Risk of Bias** is now **Critical Appraisal.**+==== 1. Navigate to Extraction ====
  
-Bear with us as we edit our documentation (don't worry, no feature functionality has changed!) and, as always, contact us at [[support@nested-knowledge.com|support@nested-knowledge.com]] if you have any questions. </WRAP>+Select "MA Extraction" from the menu:
  
-===== Configuring Data Elements =====+{{ :undefined:screenshot_2024-05-17_at_14.32.19.png?nolink |}} 
 +Alternatively, you can Extract MA data from the "MA Extract" tab in Inspector. See [[:wiki:autolit:utilities:inspector#completing_actions|here]] for details on how to get to the Study Modal.
  
-Before Extracting, you need to configure data elements. To learn how, click [[:wiki:autolit:extraction:configure|here]].+----
  
-===== Extracting Data =====+==== 2. Add Study Arms ====
  
-To learn how to extract data at the study level, click [[:wiki:autolit:extraction:extract|here]].+Study Arms represent the patient groups you plan to extract.
  
-==== Dual Extraction ====+=== 2a. Add Rows ===
  
-Using this featuretwo people can extract the same data simultaneously so that it can be adjudicated by a third party. It is analogous to how dual screening works, in that the data collected are final only after this adjudication processTo learn how to configure and carry out Dual Extraction and, click [[:wiki:autolit:extraction:dual|here]].+To add study arms and identify the Intervention used for each armclick the "+" button (red circle) in the Study Arms section of the Study Design panel (upper right)Add one Arm for every patient group from the study you plan to extract.
  
-===== Viewing and Exporting Data =====+{{ :undefined:maex7.png?nolink |}}
  
-Once you have extracted data, you can view it in [[:wiki:synthesis:quantitative|]], and [[:wiki:autolit:extraction:export|Export]] it in Custom Tables or in bulk.+=== 2bIdentify Interventions ===
  
-===== Critical Appraisal =====+Then, determine what Intervention the study investigated and then find that Intervention using the Intervention drop down menu (see above, red arrow).
  
-For any nest you extract, you may consider completing Critical Appraisal survey to reflect data quality across the studies you included in your reviewLearn how [[:wiki:autolit:risk_of_bias|here]].+=== 2c. Identify Arm Sizes === 
 + 
 +Next, determine how many participants were included in the study and put that number in the "Arm Size" box. 
 + 
 +**//Add a new Study Arm for every patient group you want to extract separately.// ** 
 + 
 +---- 
 + 
 +==== 3. Extract the Meta-Analytical Data: ==== 
 + 
 +Once you have finished establishing the Study Arms, you are ready to extract the data from the underlying study. The first step in doing so, for each Data Element, is establishing the Measurement Timepoint for each Data Element. 
 + 
 +=== 3a. Select Measurement Timepoints === 
 + 
 +Each Data Element has one Timepoint presented by default; select whether this timepoint will be: 
 + 
 +  * **Baseline: **Usually reported at the start of a study. One Baseline timepoint per Data Element will be displayed on Synthesis. 
 +  * **Outcome: **Reported at a designated follow-up period. One Outcome timepoint per Data Element will be displayed on Synthesis. 
 +  * **Other: **Any additional timepoint reported that is of interest. Any number of Other timepoints may be created and saved in AutoLit, but //**"Other" timepoints will not be presented on Synthesis.** // 
 +{{:wiki:autolit:extraction:img33.png?nolink&  }} 
 + 
 +<WRAP center round important 60%> 
 + 
 +When you designate timepoint as "Baseline" or "Outcome", you are designating that its data should be pooled with other studies' data. This means that the Measurement Timepoint you designate as "Outcome", for instance, in each study, must be similar to the "Outcome" timepoint designated in all other studies in that nest. </WRAP> 
 + 
 +=== 3b. Enter Time and Units for each Measurement Timepoint === 
 + 
 +For each Timepoint, enter the follow-up period with the appropriate unit of time (Days, Weeks, etc.). For Baseline Timepoints, this will typically be 0 days. 
 + 
 +{{:wiki:autolit:extraction:img34.png?nolink&  }} 
 + 
 +=== 3c. Extract the MA Data for each Measurement Timepoint === 
 + 
 +Read through the study and extract the relevant data scoped to each specific Timepoint. 
 + 
 +{{:wiki:autolit:extraction:img35.png?nolink&  }} 
 + 
 +=== 3d. Changes to Total Population / Loss to Follow-up === 
 + 
 +**//If the total population for any Data Element differs from the total population you reported for the Study Arm as a whole, ensure that you edit this information in the "Total" column for that individual Data Element.//  ** 
 + 
 +=== 3e. How to use Tags to inform MA Extraction === 
 + 
 +If you hover over the tag symbol on each data point (see Figure above, red circles), you will notice that the tags applied will appear. This allows for a quick and efficient way to confirm the work of the taggers, as well as the tags giving information to you as the extractor. 
 + 
 +=== 3f. How to use the "Status" symbols === 
 + 
 +**__CAUTION:__  **Watch for the red Xs that appear under "Status". This means something is wrong with the data (missing information, non-numerical information, or other error). 
 + 
 +{{:wiki:autolit:extraction:img36.png?nolink&  }} 
 + 
 +**//If any of your data elements have a red X, DO NOT hit "Complete"You will need to figure out the problem and fix it before hitting "Complete" or risk losing the data from that row.//  ** 
 + 
 +**Note:** Anytime there is a module box with the adjustable icon, you can drag to adjust the width of the box depending on your preference. 
 + 
 +{{ :wiki:autolit:extraction:width_extract.png?nolink |}} 
 + 
 +---- 
 + 
 + 
 +==== 4Complete Data Extraction ==== 
 + 
 +Once you have input all of the relevant and correct data __AND__  all of the timepoints for each Data Element you extracted have a green check mark, you can hit complete and move onto the next study!
  
  
wiki/autolit/meta_analytical_extraction/extract.1687899762.txt.gz · Last modified: 2023/06/27 21:02 by jthurnham