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wiki:synthesis:quantitative [2022/11/20 06:57] nicole_hardy_alumni.brown.edu [1. Navigate to Quantitative Synthesis] |
wiki:synthesis:quantitative [2024/09/23 12:27] (current) jthurnham [2. Explore Summary] |
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====== Quantitative Synthesis ====== | ====== Quantitative Synthesis ====== | ||
- | Quantitative Synthesis displays the results of a nest's [[: | + | Quantitative Synthesis displays the results of a nest's [[: |
+ | |||
+ | {{youtube> | ||
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==== 1. Navigate to Quantitative Synthesis ==== | ==== 1. Navigate to Quantitative Synthesis ==== | ||
From the Nest menu, click on " | From the Nest menu, click on " | ||
- | {{:wiki:synthesis: | + | {{ :undefined:circlesynth.png? |
Then, from Synthesis Home, click on the " | Then, from Synthesis Home, click on the " | ||
- | {{ :wiki:synthesis:2.png?nolink& | + | {{ :undefined:quant.png? |
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In the top-middle of the page " | In the top-middle of the page " | ||
- | {{ :wiki:synthesis:8.png?nolink& | + | {{ :undefined:screenshot_2024-09-23_at_13.17.33.png? |
=== Default Summary View === | === Default Summary View === | ||
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=== Random vs. Fixed Effects === | === Random vs. Fixed Effects === | ||
- | * **Random/ | + | * **Random/ |
+ | |||
+ | === Table vs. Visual layout === | ||
+ | |||
+ | The summary is displayed in table format to select up to three data elements to view alongside one another. You may wish to view the same data in a visual layout instead. Toggling " | ||
+ | |||
+ | While the odds ratio axes and I^2 are not provided in this summary | ||
+ | |||
+ | {{ : | ||
=== Expand Interventions === | === Expand Interventions === | ||
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In the top-middle of the page **" | In the top-middle of the page **" | ||
- | {{ :wiki:synthesis: | + | {{ :undefined:distrib.png? |
In this page, select the X and Y axes to designate the Data Elements of interest. This will generate a chart that shows the distribution of studies based on their rate of each Data Element. Furthermore, | In this page, select the X and Y axes to designate the Data Elements of interest. This will generate a chart that shows the distribution of studies based on their rate of each Data Element. Furthermore, | ||
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**Histogram view: | **Histogram view: | ||
- | {{ :wiki:synthesis:9.png?nolink& | + | {{ :undefined:dis2.png? |
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==== 4. Explore NMA ==== | ==== 4. Explore NMA ==== | ||
- | In the top-middle of the page, click " | + | To navigate to the Network Meta-analysis (NMA), in the top-middle of the page, click " |
- | {{ :wiki: | + | To explore the functions of NMA, see the [[wiki: |
- | <WRAP center round important 80%> **WARNING: | + | ==== Filtering Synthesis ==== |
- | - **Comparative Studies Only: | + | You can also apply broader filters to view specific sets of studies |
- | - **Potential Bias: | + | |
- | </ | + | |
- | === Default NMA === | + | ==== 5. Share or Embed ==== |
- | By default, your NMA page will show top-level Interventions (those just below the Root Node selected as your Interventions), | + | Similar to QLS, you can share any of the Quantitative Synthesis pages by clicking on the share icon in the top right. You have the choice of sharing via a link or downloading a QR code. |
- | == Odd Ratio Chart == | + | {{ : |
- | The Odds Ratio Chart shows all Interventions listed on both axes. The cells represent | + | If your nest is public (see Settings to do so) you will also have the option to embed QLS into a webpage. Simply copy the HTML code and paste it into your site of choice. |
- | For instance, in the diagram below, the black box displays the odds of mortality for Mechanical Thrombectomy plus IV-tPA compared to Mechanical Thrombectomy alone (0.937 : 1), while the red box displays the odds of mortality for Mechanical Thrombectomy alone with respect to Mechanical Thrombectomy plus IV-tPA (1.07 : 1), or the inverse of the red box. | + | Note: unlike in QLS, in QNS, there is no option to download a spreadsheet |
- | {{ : | + | ==== Calculation Methods for Quantitative Synthesis ==== |
- | == Selecting Data Elements and Interventions == | + | To see how statistics are calculated for Quantitative Synthesis, including for the NMA, see [[: |
- | To select the Data Element you would like to show odds for, use the drop-down in the upper right, in the "NMA Comparisons" | + | ==== Reorder or Hide Tags ==== |
- | To select | + | Since the order of dropdown options reflects |
- | {{ : | + | If you wish to hide tags in Synthesis, [[wiki:autolit:tagging:configure# |
- | + | ||
- | Once you have selected your Intervention levels, the NMA Chart will display the number of studies comparing each of your Interventions of interest. Each node represents an Intervention (hover | + | |
- | + | ||
- | == SUCRA & Forest Plot of Interventions == | + | |
- | + | ||
- | Clicking on any Row or Column will create a **SUCRA ranking**, which displays Interventions | + | |
- | + | ||
- | This will be supported by a **Forest Plot** | + | |
- | + | ||
- | == Forest Plot of Underlying Studies == | + | |
- | + | ||
- | Clicking on any cell will create a **Forest Plot** | + | |
- | + | ||
- | The cumulative Odds Ratio and 95% Confidence Interval will also be listed at the top of the page. | + | |
- | + | ||
- | {{ : | + | |
- | + | ||
- | ==== Calculation Methods for Quantitative Synthesis ==== | + | |
- | + | ||
- | To see how statistics are calculated for Quantitative | + | |