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wiki:start:demo:heart [2022/02/11 05:10]
kholub
wiki:start:demo:heart [2023/06/27 21:52] (current)
jthurnham [Extraction]
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-====== Demo Nest: ACE Inhibitors & ARBs for Heart Failure ======+====== Demo Walkthrough: ACE Inhibitors & ARBs for Heart Failure ====== 
 + 
 +Welcome to the walkthrough of the //Heart Failure: ACE Inhibitors & ARBs// demo Nest (open in your original tab). In this walkthrough, we'll explain the core functionalities of Nested Knowledge through this Nest. We encourage you to work through the Nest as you follow the walkthrough. The Nest available to you is a copy of the original and may be freely modified, so roll up your sleeves and get your hands dirty!
  
 This Nest is a copy of a previously-completed review presenting a comparison of patient outcomes from treatment of Heart Failure with Angiotensin-converting enzyme (ACE) Inhibitors and Angiotensin II Receptor Blockers (ARBs) that were reported in randomized controlled trials (RCTs). This Nest is a copy of a previously-completed review presenting a comparison of patient outcomes from treatment of Heart Failure with Angiotensin-converting enzyme (ACE) Inhibitors and Angiotensin II Receptor Blockers (ARBs) that were reported in randomized controlled trials (RCTs).
  
-In this walkthrough, we'll explain the core functionalities of Nested Knowledge through the // Heart Failure: ACE Inhibitors & ARBs //Nest. We encourage you to work through the nest as you follow this walkthrough. The nest available to you is a copy of the original and may be freely modified, so roll up your sleeves and get your hands dirty! 
 ===== Nest Home ===== ===== Nest Home =====
  
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 ===== Literature Search ===== ===== Literature Search =====
  
-The Literature Search page allows import of studies to a nest and shows where studies were sourced. This abbreviated demo Nest involves no literature searches, instead focusing on Expert RecommendationsIf you navigate to the "Literature Search" menu heading, it will show an empty table.+The Literature Search page allows import of studies to a nest and shows where studies were sourced. This demo nest **intentionally has no searches** in order to focus on demonstrating how to add records manuallySo if you navigate to the "Literature Search" menu heading, it will show an empty table.
  
 +This is typically **not standard practice for a review**, and the original completed nest did include several searches. For the purposes of this demo, all 16 studies were manually imported into screening allowing you to follow the records all the way through the workflow.
 ==== Other Sources ==== ==== Other Sources ====
  
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 Click the "Configure Study Tags" menu item to get started. Tag hierarchies consist of tags (visualized as points) and relationships between them (visualized as connecting lines). The tag hierarchy in this review includes 3 "root" tags - the highest level categories we're considering in the review. Hierarchies should be created and read as a series of "is a" relationships. For example, "Serious Adverse Event" is a "Outcome", "Acute Kidney Injury" is a "Serious Adverse Event". Hover around the hierarchy to explore tags and read off the "is a" relationships a you go. Click the "Configure Study Tags" menu item to get started. Tag hierarchies consist of tags (visualized as points) and relationships between them (visualized as connecting lines). The tag hierarchy in this review includes 3 "root" tags - the highest level categories we're considering in the review. Hierarchies should be created and read as a series of "is a" relationships. For example, "Serious Adverse Event" is a "Outcome", "Acute Kidney Injury" is a "Serious Adverse Event". Hover around the hierarchy to explore tags and read off the "is a" relationships a you go.
  
-{{:wiki:start:heart_tag_config.png?nolink&700}}+{{ :wiki:start:demo:demo3.png?nolink |}}
  
 ==== Tagging Module ==== ==== Tagging Module ====
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 ===== Extraction ===== ===== Extraction =====
  
-Please see our [[:wiki:autolit:extraction|Extraction Documentation]] page to review how Extraction was configured for this Nest. Click the Extraction menu item to view and perform Extraction for this review.+Please see our [[:wiki:autolit:meta_analytical_extraction|Extraction Documentation]] page to review how Extraction was configured for this Nest. Click the Extraction menu item to view and perform Extraction for this review.
  
 {{:wiki:start:heart_extraction.png?nolink&700}} {{:wiki:start:heart_extraction.png?nolink&700}}
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 ===== Synthesis ===== ===== Synthesis =====
  
-At this point, we've reviewed all the evidence gathered in AutoLit for the //Heart Failure: ACE Inhibitors & ARBs//// // Nest. Now let's navigate to Synthesis Home to draw some conclusions from our evidence, by clicking the Synthesis menu heading.+At this point, we've reviewed all the evidence gathered in AutoLit for the //Heart Failure: ACE Inhibitors & ARBs// Nest. Now let's navigate to Synthesis Home to draw some conclusions from our evidence, by clicking the Synthesis menu heading.
  
 {{:wiki:start:heart_synthesis_home.png?nolink&700}} {{:wiki:start:heart_synthesis_home.png?nolink&700}}
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 Navigate back to Synthesis Home and click the Quantitative Synthesis box. Quantitative Synthesis (QNS) displays data gathered in the Extraction Module. QNS contains 3 different analyses automatically computed from extracted data. Navigate back to Synthesis Home and click the Quantitative Synthesis box. Quantitative Synthesis (QNS) displays data gathered in the Extraction Module. QNS contains 3 different analyses automatically computed from extracted data.
  
-The Summary tab contains pooled estimates of outcomes, broken out by interventions. Interventions may be expanded to different levels of precision, while outcomes analyzed may be selected from the dropdown menus. In the below example, we find a 17.6% mortality rate for Placebo against generally lower rates for other medications; Omecamtiv m <font inherit/inherit;;inherit;;inherit>ecarbil carries a 25.9% mortality rate, but the estimate is only built on a single, albeit large, study.</font>+The Summary tab contains pooled estimates of outcomes, broken out by interventions. Interventions may be expanded to different levels of precision, while outcomes analyzed may be selected from the dropdown menus. In the below example, we find a 17.6% mortality rate for Placebo against generally lower rates for other medications; Omecamtiv m ecarbil carries a 25.9% mortality rate, but the estimate is only built on a single, albeit large, study.
  
 {{:wiki:start:heart_qns_summary.png?nolink&700}} {{:wiki:start:heart_qns_summary.png?nolink&700}}
wiki/start/demo/heart.1644556251.txt.gz · Last modified: 2022/02/11 05:10 by kholub