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wiki:synthesis:quantitative [2022/11/21 20:53] kevinkallmes [4. Explore NMA] |
wiki:synthesis:quantitative [2023/09/12 11:21] jthurnham [5. Share, Embed or Download] |
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====== Quantitative Synthesis ====== | ====== Quantitative Synthesis ====== | ||
- | Quantitative Synthesis displays the results of a nest's [[: | + | Quantitative Synthesis displays the results of a nest's [[: |
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+ | {{youtube> | ||
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==== 1. Navigate to Quantitative Synthesis ==== | ==== 1. Navigate to Quantitative Synthesis ==== | ||
From the Nest menu, click on " | From the Nest menu, click on " | ||
- | {{:wiki:synthesis: | + | {{ :undefined:circlesynth.png? |
Then, from Synthesis Home, click on the " | Then, from Synthesis Home, click on the " | ||
- | {{ :wiki:synthesis:2.png?nolink& | + | {{ :undefined:quant.png? |
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In the top-middle of the page **" | In the top-middle of the page **" | ||
- | {{ :wiki:synthesis: | + | {{ :undefined:distrib.png? |
In this page, select the X and Y axes to designate the Data Elements of interest. This will generate a chart that shows the distribution of studies based on their rate of each Data Element. Furthermore, | In this page, select the X and Y axes to designate the Data Elements of interest. This will generate a chart that shows the distribution of studies based on their rate of each Data Element. Furthermore, | ||
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**Histogram view: | **Histogram view: | ||
- | {{ :wiki:synthesis:9.png?nolink& | + | {{ :undefined:dis2.png? |
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==== 4. Explore NMA ==== | ==== 4. Explore NMA ==== | ||
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+ | To navigate to the Network Meta-analysis (NMA), in the top-middle of the page, click " | ||
To explore the functions of NMA, see the [[wiki: | To explore the functions of NMA, see the [[wiki: | ||
- | In the top-middle of the page, click " | + | ==== 5. Share or Embed ==== |
- | {{ : | + | Similar to QLS, you can share any of the Quantitative Synthesis pages by clicking on the share icon in the top right. You have the choice of sharing via a link or downloading a QR code. |
- | <WRAP center round important 80%> **WARNING:** The automatically-generated Network Meta-analysis uses generally accepted practices to calculate odds ratios and other outputs. However, you should use and interpret these findings with care: | + | {{ :undefined:qns_ambed.png? |
- | - **Comparative Studies Only: | + | If your nest is public (see Settings to do so) you will also have the option to embed QLS into a webpage. Simply copy the HTML code and paste it into your site of choice. |
- | - **Potential Bias: | + | |
- | </ | + | |
- | === Default NMA === | + | Note: unlike in QLS, in QNS, there is no option to download a spreadsheet of filtered studies from Synthesis. Only nest users can access this data in Study Inspector --> Download --> MA Extraction. |
- | By default, your NMA page will show top-level Interventions (those just below the Root Node selected as your Interventions), | + | ==== Calculation Methods for Quantitative Synthesis ==== |
- | == Odd Ratio Chart == | + | To see how statistics are calculated for Quantitative Synthesis, including for the NMA, see [[: |
- | The Odds Ratio Chart shows all Interventions listed on both axes. The cells represent the odds ratio between the Intervention displayed in the row and the Intervention displayed in the column. | + | ==== Reorder or Hide Tags ==== |
- | For instance, | + | Since the order of dropdown options reflects the order of tags in the tagging hierarchy, you may wish to reorder these tags. See instructions on [[wiki:autolit: |
- | {{ : | + | If you wish to hide tags in Synthesis, [[wiki:autolit:tagging: |
- | + | ||
- | == Selecting Data Elements and Interventions == | + | |
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- | To select the Data Element | + | |
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- | To select the level of analysis for Interventions, | + | |
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- | {{ :wiki:synthesis:10.png? | + | |
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- | Once you have selected your Intervention levels, the NMA Chart will display the number of studies comparing each of your Interventions of interest. Each node represents an Intervention (hover to see the Intervention title), and each line represents the number of studies comparing any two nodes. | + | |
- | + | ||
- | == SUCRA & Forest Plot of Interventions == | + | |
- | + | ||
- | Clicking on any Row or Column will create a **SUCRA ranking**, which displays Interventions in order based on their odds of achieving a given outcome. So, if high odds represent patient benefit, the 1st Intervention in the ranking represents a preliminary estimate of where that Intervention ranks in terms of patient benefit. | + | |
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- | This will be supported by a **Forest Plot** | + | |
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- | == Forest Plot of Underlying Studies == | + | |
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- | Clicking on any cell will create a **Forest Plot** | + | |
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- | The cumulative Odds Ratio and 95% Confidence Interval | + | |
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- | {{ : | + | |
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- | ==== Calculation Methods for Quantitative Synthesis ==== | + | |
- | + | ||
- | To see how statistics are calculated for Quantitative Synthesis, including for the NMA, see [[: | + | |