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wiki:synthesis:quantitative:methods [2022/06/30 17:51] kholub |
wiki:synthesis:quantitative:methods [2023/09/07 12:56] (current) jthurnham [Data Analyzed] |
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===== Data Analyzed ===== | ===== Data Analyzed ===== | ||
- | Any study included (adjudicated, | + | Any study included (adjudicated, |
===== Analyses ===== | ===== Analyses ===== | ||
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For medians, pooled estimates & inferentials are computed as the Weighted Median of Medians, described in [[https:// | For medians, pooled estimates & inferentials are computed as the Weighted Median of Medians, described in [[https:// | ||
- | All computational methods are implemented as a transcription, | + | === Sources of Computational Methods === |
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+ | All computational methods are implemented as a transcription, | ||
==== Network Meta-Analysis (NMA) ==== | ==== Network Meta-Analysis (NMA) ==== | ||
- | Any multi-arm study with two or more arms extracted are analyzed in NMA. If the user-configured intervention grouping assigns the same intervention to two or more arms in the study, they are pooled; if it assigns the same intervention to all arms in the study, the study is discarded from the NMA. | + | Any multi-arm study with two or more arms extracted are analyzed in NMA. If the user-configured intervention grouping assigns the same intervention to two or more arms in the study, they are pooled; if it assigns the same intervention to all arms in the study, the study is discarded from the NMA. Only continuous data elements with mean & SD configured, or dichotomous data elements are eligible for NMA; arms where SD is not extracted are discarded from the analysis. |
Before performing the NMA, connected components of the intervention graph are identified. Each connected component is analyzed in a separate NMA, and the results of the NMAs are combined in outputs and visuals. No effect estimates will be provided for interventions that belong to different connected components. | Before performing the NMA, connected components of the intervention graph are identified. Each connected component is analyzed in a separate NMA, and the results of the NMAs are combined in outputs and visuals. No effect estimates will be provided for interventions that belong to different connected components. | ||
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+ | Direct effects are computed as Mean Differences (continuous data elements) or Odds Ratios (dichotomous data elements) between all pairs of within-study arms. Consistent indirect effects are computed using the Aitken estimator (described in [[https:// | ||
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+ | Funnel plots are generated using all contrasts available on the selected intervention. " | ||
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+ | === Sources of Computational Methods === | ||
+ | |||
+ | All computational methods are implemented as a transcription, | ||