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wiki:synthesis:quantitative:explorenma

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wiki:synthesis:quantitative:explorenma [2022/11/28 02:19]
nicole_hardy_alumni.brown.edu 		wiki:synthesis:quantitative:explorenma [2023/06/06 19:58] (current)
jthurnham
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 **To navigate to NMA:** In the top-middle of the page, click "NMA". **To navigate to NMA:** In the top-middle of the page, click "NMA".
  
-{{  :wiki:synthesis:screenshot2022-09-26154022.png?nolink&  }}+{{ :undefined:nmaaaaa.png?nolink |}}
  
 <WRAP center round important 80%> **WARNING:** The automatically-generated Network Meta-analysis uses generally accepted practices to calculate odds ratios and other outputs. However, you should use and interpret these findings with care: <WRAP center round important 80%> **WARNING:** The automatically-generated Network Meta-analysis uses generally accepted practices to calculate odds ratios and other outputs. However, you should use and interpret these findings with care:
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 For instance, in the diagram below, the black box displays the odds of mortality for Mechanical Thrombectomy plus IV-tPA compared to Mechanical Thrombectomy alone (0.929 : 1), while the red box displays the odds of mortality for Mechanical Thrombectomy alone with respect to Mechanical Thrombectomy plus IV-tPA (1.08 : 1), or the inverse of the red box. For instance, in the diagram below, the black box displays the odds of mortality for Mechanical Thrombectomy plus IV-tPA compared to Mechanical Thrombectomy alone (0.929 : 1), while the red box displays the odds of mortality for Mechanical Thrombectomy alone with respect to Mechanical Thrombectomy plus IV-tPA (1.08 : 1), or the inverse of the red box.
  
-{{:wiki:synthesis:quantitative:image4.png?nolink&  }}+{{ :undefined:nmaaaci.png?nolink |}}
  
 === I squared === === I squared ===
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 In addition to Odds Ratios, the [[https://www.statsdirect.com/help/meta_analysis/heterogeneity.htm|I squared value]] for the NMA comparison is presented upon hover over the three-box icon: In addition to Odds Ratios, the [[https://www.statsdirect.com/help/meta_analysis/heterogeneity.htm|I squared value]] for the NMA comparison is presented upon hover over the three-box icon:
  
-{{:wiki:synthesis:quantitative:image5.png?nolink&  }}+{{ :undefined:i2.png?nolink |}}
  
 This will present the I squared value representing the expected impact of heterogeneity on findings (from 0 to 100%), with a 95% Confidence Interval. This will present the I squared value representing the expected impact of heterogeneity on findings (from 0 to 100%), with a 95% Confidence Interval.
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 To **compare an individual Intervention to all other Interventions**  displayed in the Odds Ratio chart, select its title from either the row or column headers. To **compare an individual Intervention to all other Interventions**  displayed in the Odds Ratio chart, select its title from either the row or column headers.
  
-{{:wiki:synthesis:quantitative:image6.png?nolink&  }}+{{ :undefined:comparei2.png?nolink |}}
  
 This will give you access to the following graphs (which you can exit by clicking "**close**" in the upper left): This will give you access to the following graphs (which you can exit by clicking "**close**" in the upper left):
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 By default, you will see a **Forest Plot**  displaying the Odds Ratio and a 95% Confidence Interval for the Intervention chosen compared to all other Interventions in the Odds Ratio Chart: By default, you will see a **Forest Plot**  displaying the Odds Ratio and a 95% Confidence Interval for the Intervention chosen compared to all other Interventions in the Odds Ratio Chart:
  
-{{:wiki:synthesis:quantitative:image7.png?nolink&  }}+{{ :undefined:foresti2.png?nolink |}}
  
 === SUCRA === === SUCRA ===
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 Toggling to SUCRA in the top middle will display a **SUCRA ranking**, which displays Interventions in order based on their odds of achieving a given outcome. So, if high odds represent patient benefit, the 1st Intervention in the ranking represents a preliminary estimate of where that Intervention ranks in terms of patient benefit. Toggling to SUCRA in the top middle will display a **SUCRA ranking**, which displays Interventions in order based on their odds of achieving a given outcome. So, if high odds represent patient benefit, the 1st Intervention in the ranking represents a preliminary estimate of where that Intervention ranks in terms of patient benefit.
  
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 === Funnel Plot === === Funnel Plot ===
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   * Since there may be more than one comparator, different Interventions being compared against your selected Intervention are displayed in different colors.   * Since there may be more than one comparator, different Interventions being compared against your selected Intervention are displayed in different colors.
   * A triangle is formed indicating the estimated range in which 95% of studies are expected to lie.   * A triangle is formed indicating the estimated range in which 95% of studies are expected to lie.
-  * Additionally, an [[https://training.cochrane.org/resource/identifying-publication-bias-meta-analyses-continuous-outcomes|Egger's test]] is run to test asymmetry and the findings are shown at to top of the Funnel Plot.+  * Additionally, an [[https://training.cochrane.org/resource/identifying-publication-bias-meta-analyses-continuous-outcomes|Egger's test]] is run to test asymmetry and the findings are shown at the top of the Funnel Plot.
  
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 ==== Forest Plot of Underlying Studies ==== ==== Forest Plot of Underlying Studies ====
wiki/synthesis/quantitative/explorenma.1669601955.txt.gz · Last modified: 2022/11/28 02:19 by nicole_hardy_alumni.brown.edu

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