This Nest is a copy of a previously-completed review presenting the evidence regarding the safety and efficacy of anti-virals that had randomized controlled trial (RCT) evidence reported in the treatment of COVID-19 as of January 2021.

In this walkthrough, we'll explain the core functionalities of Nested Knowledge through the COVID-19: Antivirals Nest. We encourage you to work through the nest as you follow this walkthrough. The nest available to you is a copy of the original and may be freely modified, so roll up your sleeves and get your hands dirty!

You've landed on your demo Nest in AutoLit, and you're looking at the Nest Home page. This page includes a menu on the left of the page, the protocol in the center, and discussion about the Nest on the right. The menu includes links to all modules & configurations available to you in AutoLit. We'll now walk through these modules one by one. (click the title in the menu to navigate to the the corresponding module).

The Literature Search page allows import of studies to a nest and shows where studies were sourced. This review includes two searches - an API-based (automatic integration) search of PubMed and a file-based import from Embase. Hover and click the “History and Details” column to see greater detail about the searches, including when they were run and any query structuring available. The PubMed search is API-based and may be run on demand. Hover the Pubmed row and click the “Run” button to update this search- you may import some new records!

Records may be imported through other means. Click the “Other Sources” menu item under “Literature Search” to view records that were individually added as expert recommendations. 19 such studies were imported into this Nest. Try importing the DOI or PMID of your favorite study using the “Add by Identifier” form on the right of the page.