This guide provides instructions and tips on best practices for conducting systematic reviews and meta-analyses. The information presented in this guide applies to reviews conducted with Nested Knowledge or with other methods.

A systematic review is a summary of medical literature related to a particular research question.

The first steps to conducting a systematic review include planning questions you must answer. Mainly, is this review feasible to complete?

Use the Nested Knowledge software to conduct a systematic review or use external methods.

Making sure your extracted data is accurate and your included studies are all high quality are the two foundations for conducting quality control.

When thinking about writing the manuscript, you must find a target journal that is likely to accept your manuscript.

Begin writing up your introduction, abstract, methods, results, and discussion sections of the manuscript.

All journals have formatting requirements before you can submit your materials for possible publication.

The final step in conducting a systematic review is to Tips for Submitting Your Manuscript your completed and QC'ed manuscript to the target journal.