This guide provides instructions and tips on best practices for conducting systematic reviews. The information presented in this guide applies to reviews conducted with or without Nested Knowledge.

A systematic review is a summary of medical literature related to a particular research question.

You will want to carefully plan your systematic review. Mainly, is this review feasible to complete? Should you register your protocol?

Use the Nested Knowledge software to conduct a systematic review or use external methods.

Quality control is necessary to ensure that your extracted data are accurate and your included studies are all high quality.

When thinking about writing the manuscript, you must find a target journal that is likely to accept your manuscript.

Begin writing up your introduction, abstract, methods, results, and discussion sections of the manuscript.

All journals have formatting requirements before you can submit your materials for possible publication.

The final step in conducting a systematic review is to Tips for Submitting Your Manuscript your completed and QC'ed manuscript to the target journal.